Sport-related injuries are a substantial concern. Inflammation and pain play primary roles with respect to recovery. Hyperbaric oxygen therapy (HBOT) has been shown to significantly reduce inflammation and ameliorate pain. Hyperbaric Oxygen Therapy can promote fibroblast/collagen activity to accelerate and enhance healing from surgeries and wounds. New evidence supports HBOT as an adjunct and practical treatment to help moderate the effects of traumatic brain injuries and enhance SPECT imaging results.